Research Progress on Extraction, Purification, and Bioactivities of Anthocyanidins from Mulberry

Mulberry anthocyanins, recognized as significant natural pigments and functional constituents, have garnered substantial interest due to their diverse biological activities, particularly in the areas of antioxidant, anti-inflammatory, and antitumor effects. Recent advancements in extraction and purification methodologies for mulberry anthocyanins have resulted in the development of various highly efficient extraction techniques. These innovations not only enhance extraction yields but also preserve the bioactivity of the anthocyanins. Concurrently, the application of purification technologies, including macroporous resin and high-performance preparative liquid chromatography, has improved the purity of anthocyanins, thereby augmenting their applicability in pharmaceutical contexts. This study aims to review the most recent advancements in the extraction and purification of mulberry anthocyanins and to discuss research findings related to antioxidant, anticancer, anti-inflammatory, and other bioactivities. The insights provided herein are intended to offer both theoretical foundations and practical guidance for the effective utilization and industrialization of anthocyanins in the future.