Physical Growth and Neurodevelopmental Indicators at Corrected 6 Months of Age in Preterm Infants Born at 22-32 Weeks Gestation: A Single-Center Study

Objective To investigate the physical growth and neurodevelopmental indicators of Gestational age（GA）＜ 32 weeks infants at 6 months corrected age. Methods This study included 116 infants, retrospectively analyzing GA＜32 weeks infants who discharged from Tianjin Central Hospital of Gynecology and Obstetrics between April 2023 and August 2024. General movements (GMs) assessment was performed at 1 month corrected age. Physical Growth Indicators, GMs and Gesell Developmental Diagnosis Scale (GDDS) assessments were conducted at 3 and 6 months corrected age. Results The proportion of abnormal GMs at 3 months corrected age (86.21%) was lower than that at 1 month corrected age (3.44%).At 6 months corrected age, the proportion of infants with a developmental quotient (DQ) ≤75 was 43.10%, lower than 69.82% at 3 months corrected age. GA and multiple births were independent risk factors for DQ ≤75 at 3 months corrected age. Gestational age, early intervention, and intracranial hemorrhage were independent risk factors for DQ ≤75 at 6 months corrected age. Conclusion At 6 months corrected age, GA＜32 weeks infants exhibited greater neurodevelopmental outcome. Standardized follow-up and early neurodevelopmental interventions should be further strengthened for preterm infants to reduce the occurrence of adverse outcomes.