Effects of Selenium Deficiency on Electrocardiogram and Oxidative Stress Level of Pregnant Women and Neonates in Northeast China

Background Selenium deficiency is a critical health concern, this project was studied for its impact on ECG parameters and oxidative stress in women (pregnant & non-pregnant) and neonates. Methods A cohort of 1515 women and 200 neonates from contrasting selenium status regions underwent ECG evaluations, selenium content determination and oxidative stress level assessments. Results Through the application of relevant kit detection, study revealed lower selenium & heightened oxidative stress level in deficient groups (P < 0.01). Pregnant women from deficient regions exhibited prolonged ECG intervals, whereas non-pregnant showed reduced intervals. Neonates with selenium deficiency manifested altered ECG waves. Animal models are consistent with human studies, confirming ECG abnormalities & oxidative stress exacerbation in selenium scarcity. Conclusions Our results imply that inadequate selenium intake may not only perturb the intricate balance of oxidative stress but also precipitate alterations in ECG patterns, thereby posing potential risks to cardiovascular health.